MODY1 - A New Type Of Diabetes?

A new study suggests that there is a type of diabetes dubbed maturity-onset diabetes of the young-- or, MODY1. This type is often diagnosed and treated as type 2 diabetes, to the patient’s detriment.

What Is MODY1

MODY1 is a rare form of diabetes that is strongly genetic and caused by a mutated gene. Only 3 to 5 percent of diabetics are MODY1. Onset is usually before the age of 25, and insulin may not be necessary.

According to the 'Journal of Biological Chemistry,' MODY1 symptoms are similar to type 2 diabetics, so people with MODY1 might be treated as a type 2 diabetic. This is not good.

The Problem with Misdiagnosis

Type 2 diabetics are often treated with oral medications that lower insulin resistance. With MODY1, these oral medications actually kill beta cells. Beta cells are responsible for the production of insulin, so destroying them results in the patient becoming insulin dependent. Because of this, it can be detrimental for someone with MODY1 to be misdiagnosed as a type 2 diabetic.

"It's important to diagnose patients as accurately as possible and to attempt to target the correct pathway," said Benjamin Moore, study lead author.

Photo: AMSNY